Clinical Trials & Scientific Studies in Homeopathy

Below is a curated selection of peer-reviewed research exploring clinical outcomes, laboratory findings, mechanisms, and observational data related to homeopathic medicine. Each entry links directly to the published study.

Human Clinical Trials

Individualized Homeopathic Medicines in Stage I Essential Hypertension

Double-blind, randomized, placebo-controlled pilot trial evaluating blood pressure outcomes.
https://pubmed.ncbi.nlm.nih.gov/33662951/

Individualized Homeopathic Medicines in Generalized Anxiety Disorder

Pilot randomized controlled trial assessing anxiety score improvements.
https://pubmed.ncbi.nlm.nih.gov/33662951/

Preventing Progression From Pre-hypertension to Hypertension

Randomized controlled trial examining whether individualized remedies slow disease progression.
https://pubmed.ncbi.nlm.nih.gov/34147344/

Homeopathy for Atopic Dermatitis in Adults

Preliminary double-blind RCT observing symptom reduction and quality-of-life changes.
https://pubmed.ncbi.nlm.nih.gov/33857943/

Homeopathy for Cutaneous Warts

Pilot RCT evaluating individualized prescriptions vs placebo.
https://pubmed.ncbi.nlm.nih.gov/33761570/

Homeopathy for Plantar Fasciitis

Double-blind RCT measuring pain reduction and functional improvement.
https://pubmed.ncbi.nlm.nih.gov/34492725/

Individualized Homeopathy for Primary Dysmenorrhea

Randomized controlled trial assessing menstrual pain and symptom scores.
https://www.hri-research.org/2022/05/randomised-controlled-trials-data-update-2021/

Homeopathy for Insomnia

Double-blind RCT evaluating sleep duration and quality outcomes.
https://pubmed.ncbi.nlm.nih.gov/30935555/

Premenstrual Syndrome: Symptom-Cluster-Based Homeopathic Treatment

Double-blind RCT investigating individualized remedies for PMS relief.
https://www.ncbi.nlm.nih.gov/m/pubmed/31434111/

Hot Flashes in Menopause (Capsicum frutescens Trial)

Phase-2 RCT assessing symptom frequency and severity in menopausal women.
https://www.ncbi.nlm.nih.gov/pubmed/30736083

Endometriosis-Associated Pelvic Pain

Randomized, double-blind trial evaluating potentized estrogen’s effect on pain scores.
http://www.ejog.org/article/S0301-2115(17)30060-X/abstract

Depression in Peri- and Post-Menopausal Women

Double-blind, placebo-controlled RCT comparing individualized homeopathy and fluoxetine.
http://www.ncbi.nlm.nih.gov/pubmed/25768800

Homeopathy for Chronic Tension-Type Headache

Pragmatic RCT assessing frequency and intensity of headaches.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620378/

Otitis Media in Children — Homeopathy vs Conventional Treatment

Randomized pilot study comparing resolution time and symptom severity.
http://www.ncbi.nlm.nih.gov/pubmed/22226309

Flu, Fever, Cough, Diarrhea (Multiple Acute Conditions)

Meta-analysis and RCTs showing outcomes in childhood diarrhea and acute infections.
http://www.ncbi.nlm.nih.gov/pubmed/12634583

Influence of Homeopathy on Cancer Patient Well-Being

Pragmatic RCT measuring global health status and subjective well-being.
http://www.ncbi.nlm.nih.gov/pubmed/26051564

Homeopathy as Add-On Therapy in Non-Small Cell Lung Cancer

Multicenter, double-blind study suggesting improved quality of life and survival.
https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13548

Homeopathic Ear Drops for Otitis Media

Adjunctive RCT showing symptomatic relief in children.
http://www.ncbi.nlm.nih.gov/pubmed/21784326

Veterinary Clinical Trials

Arnica montana 30cH for Post-Operative Pain in Dogs

Double-blind placebo-controlled study after elective spay surgery.
https://pubmed.ncbi.nlm.nih.gov/34781409/

Homeopathy for Diarrhea in Piglets

Trial comparing individualized remedies to antibiotics for E. coli diarrhea.
https://www.ncbi.nlm.nih.gov/pubmed/20129177

Homeopathic Treatment for Intestinal Parasites in Fish

Study evaluating immune response and reduction of coccidia.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0039-1681062

Homeopathy in Feline & Canine Chronic Conditions

Real-world prescribing study on outcomes for companion animals.
http://www.ncbi.nlm.nih.gov/pubmed/20970093

Laboratory, Cellular & Mechanistic Research

Low-Dose Drosera rotundifolia and Gene Expression

In vitro study showing measurable gene expression changes in bronchial cells.
https://www.nature.com/articles/s41598-021-81843-y

Arnica montana & Bellis perennis in Breast Reconstruction Surgery

Randomized trial demonstrating reduced seroma formation.
https://link.springer.com/article/10.1007/s00238-019-01618-7

Hormesis, Nanopharmacology & Ultra-High Dilutions

Review exploring possible physicochemical mechanisms of action.
https://journals.sagepub.com/doi/10.1177/15593258211022983

Arnica Montana 30C Reduces DNA Damage in E. coli

Study suggesting up-regulation of DNA repair genes under UV stress.
https://www.ncbi.nlm.nih.gov/pubmed/22409925

Symphytum officinale and Osteogenesis

In vitro study showing enhanced bone-forming activity in stem cells.
https://www.sciencedirect.com/science/article/pii/S0378874119331216

Lycopodium, Hydrastis, Terminalia — Anticancer Cellular Research

Multiple in-vitro studies showing apoptosis, growth inhibition, and epigenetic effects.
https://www.ncbi.nlm.nih.gov/pubmed/23972240
http://www.sciencedirect.com/science/article/pii/S1475491616000151
http://www.ncbi.nlm.nih.gov/m/pubmed/26559365/

NMR & Spectroscopy Characterization of Potentized Medicines

Studies showing structural differences between potencies and controls.
https://www.ncbi.nlm.nih.gov/pubmed/29157472
http://www.ncbi.nlm.nih.gov/pubmed/19474239

Voltage Generation in Potentized Remedies

Raman spectroscopy investigation into physicochemical changes.
https://www.ncbi.nlm.nih.gov/pubmed/30616251

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Observational Studies & Case Series

Attention Dysregulation in Breast Cancer Patients

Double-blind trial assessing cognitive effects of adjunctive treatment.
https://pubmed.ncbi.nlm.nih.gov/34027702/

Appearance of Acute Inflammatory State Indicates Improvement in Atopic Dermatitis

Case series suggesting “healing crises” may signal positive trajectory.
https://journals.sagepub.com/doi/full/10.1177/1179547621994103

Antimonium Crudum in Pediatric Skin Conditions

Clinical case series reporting improvements in dermatologic symptoms.
https://onlinelibrary.wiley.com/doi/full/10.1002/ccr3.3674

Multimorbidity After Surgical Menopause

Case report demonstrating broad symptom improvement.
https://journals.sagepub.com/doi/full/10.1177/1179547620965560

Myasthenia Gravis Therapy

Case report highlighting symptom stabilization with individualized homeopathy.
https://onlinelibrary.wiley.com/doi/full/10.1002/ccr3.3190

COVID-19 Symptomatic Patients Treated by Homeopathic Physicians

Descriptive Italian observational study.
https://www.researchgate.net/publication/340631586

Chronic Constipation — Pilot Study

Open-label study assessing individualized treatment response.
https://hpathy.com/scientific-research/a-pilot-study-of-individualised-homeopathic-treatment-of-chronic-constipation/

Fibromyalgia Improvements With Individualized Remedies

RCT showing significant improvement compared to placebo.
http://rheumatology.oxfordjournals.org/content/43/5/577.abstract

Cancer Cohorts Treated With Classical Homeopathy

Prospective observational study across two independent cohorts.
http://www.ncbi.nlm.nih.gov/pubmed/21241504

Long-Term Health Outcomes After Homeopathic Treatment

Eight-year follow-up study showing sustained improvement in chronic illness.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630323/

Health Economics, Usage & Perception Studies

Outcome & Cost Comparison of Homeopathic and Conventional Medicine

Large cohort study analyzing healthcare utilization and cost differences.
https://www.ncbi.nlm.nih.gov/pubmed/16036164

Swiss Insurance Cost Comparison

Study reviewing economic outcomes of complementary vs conventional care.
http://www.ncbi.nlm.nih.gov/pubmed/22189362

Perceptions of Homeopathy in Supportive Cancer Care (France)

Survey of oncologists and GPs on integration of homeopathy.
https://pubmed.ncbi.nlm.nih.gov/33763723/

Parent Demand for Integrative Pediatrics (Germany)

Survey showing high self-pay willingness for integrative therapies.
https://pubmed.ncbi.nlm.nih.gov/34246995/

Reviews & Meta-Analyses

Analysis of Four Government-Funded Reviews of Homeopathic Medicine

Critical review highlighting methodology and interpretations.
https://www.cureus.com/articles/62105

Systematic Review of Homeopathic Clinical Trial Quality

Assessment of design, bias, and reporting quality across RCTs.
http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-1-12

Meta-Analysis of Homeopathic Studies

Overview summarizing outcomes across multiple controlled trials.
http://www.britishhomeopathic.org/wp-content/uploads/2013/05/evidencesummary.pdf

Homeopathy & Malaria Research: Review

Compilation of peer-reviewed excerpts focused on malaria models.
http://researchinhomeopathy.org/homeopathy-and-malaria-research-peer-reviewed-excerpts-and-links/

 

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